AstraZeneca's Multi-Agent System: Lessons Scaling Agents by 10x With Agent Bricks

AstraZeneca built a multi-agent system using Agent Bricks to transform how commercial teams access pharmaceutical data. The Brand Assistant uses a supervisor agent coordinating specialized sub-agents across therapeutic areas, combining structured data via Genie Spaces with unstructured documents via Knowledge Assistant.

Unity Catalog integration with Entra ID enforces strict permission boundaries. MCP unlocks third-party tool integration.The architecture scaled from 5-agent POC to 20+ agents in production, designed for 50+.

Key components:

• Multi-Agent Supervisor for orchestration
• Genie Spaces for NL-to-SQL
• Knowledge Assistant for documents
• Unity Catalog for row/column-level security
• MLflow for tracing.

This session covers:

• Multi-agent architecture patterns
• Permission-preserving design
• When to split supervisors vs. add agents
• Human-in-the-loop testing
• Why bad data breaks agents regardless of tech
• Organizational challenges of agent ownership
• Lessons from scaling